Long Sleep Hours Linked to Higher Alzheimer's Protein Levels, UT Health San Antonio Study Finds

July 16, 2026 - 22:30

A new study from UT Health San Antonio has uncovered a concerning connection between sleeping long hours and increased levels of a protein associated with Alzheimer's disease. Researchers found that people who regularly sleep more than nine hours per night tend to have higher amounts of amyloid-beta in their brains, a protein that forms the sticky plaques characteristic of Alzheimer's.

The study, which analyzed data from older adults, suggests that excessive sleep may be more than just a lifestyle quirk. It could signal underlying brain changes or even contribute to the disease process itself. The team measured amyloid levels using brain imaging and compared them with self-reported sleep durations. Those who slept the longest showed significantly more protein buildup.

This does not mean that long sleep causes Alzheimer's. The relationship could go both ways. Early brain changes related to the disease might disrupt sleep patterns, leading people to sleep longer. Alternatively, too much sleep might reduce the brain's ability to clear out waste proteins during waking hours.

The findings add to a growing body of research linking sleep disturbances to dementia risk. Previous studies have focused on short sleep or poor quality sleep. This one highlights that too much sleep may carry its own risks.

Experts recommend that adults aim for seven to nine hours of sleep per night. Anyone sleeping consistently beyond that range should talk to a doctor. The study underscores the importance of monitoring sleep habits as part of overall brain health.